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This application is to extend our current XSEDE allocation (TG-MCB170036) and ECSS support to allow us to move the science gateway (https://www.searchsra.org/) that we built with our startup allocation to the next level. Using our initial allocation we deployed a proof-of-concept science gateway that has been used by a small cadre of scientists to generate significant preliminary data and to demonstrate the utility of the platform. With the new allocation, we will extend the number of users that are accessing the science gateway, and continue to improve the service that we provide. We will continue to work with end-users to ensure that their questions are addressed and the science gateway improved. In addition, we will work with other scientists who wish to have computational access to the sequence read archive data.

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